Hypohydration effects on skeletal muscle performance and metabolism: a 31P-MRS study

Ten physically active volunteers (age 21–40 yr) performed supine single-leg, knee-extension exercise to exhaustion in a 1.5-T whole body magnetic resonance spectroscopy (MRS) system when euhydrated and when hypohydrated (4% body wt). Time to fatigue was reduced (P , 0.05) by 15% when the subjects were hypohydrated.

Hypohydration effects on skeletal muscle performance and metabolism: a 31P-MRS study